With health care expenditures constituting more than 17 percent of the U.S. gross domestic product, lawmakers and physicians continue to search for ways to control costs while providing effective, evidence-based care.

The ABIM Foundation asked each partnering society to review its current practices and suggest five items that, based on the latest evidence on disease management and treatment, are overused or misused or could jeopardize patient safety and care. Each society submitted its list of Five Things Physicians and Patients Should Question.

A 10-minute bedside test of frailty can predict the likelihood of delayed graft function (DGF) in patients undergoing kidney transplants, according to a new study in the Archives of Surgery. Frailty has emerged as an important characteristic of health state in the elderly, but in this study, the effect of frailty on DGF was independent of age.

The scientific spotlight in genomics research is no longer aimed solely at DNA. It is now being shared with DNA regulatory elements such as microRNAs (miRNAs), a family of small, noncoding RNAs that control gene expression by inhibiting translation of their target RNAs.

The national rollout of CROWNWeb for all federally certified dialysis clinics will soon be complete, according to the Centers for Medicare & Medicaid Services (CMS).

The number of physicians employed by hospitals or medical groups continues to increase, reflecting changing trends in physician reimbursement and pay-for-performance models as well as the increased infrastructure to support ongoing changes.

Health care reimbursement is undergoing a fundamental change from volume-driven to value-driven care. The Patient Protection and Affordable Care Act of 2008 has marshaled this transformation in the dominant payment model. This legislation, as yet unproven in its benefits, has placed disproportionate burdens on medical practices, challenging the business models on which they are built.