Brenner Lectureship to Cover Novel Diabetes Therapy

Jeff M. Sands

/kidneynews/7_10_11/34a/graphic/34af1.jpg

A well-known Emory University researcher will present the Barry M. Brenner, MD, Endowed Lectureship on “Novel Therapy for Diabetes Insipidus” on Sunday, Nov. 8.

Jeff M. Sands, MD, is the Juha P. Kokko Professor of Medicine and Physiology and director of the renal division at Emory University School of Medicine. He served as executive vice chair of medicine at Emory from 2009 to 2015 and as associate dean for clinical and translational research from 2006 to 2010.

Dr. Sands’ research is directed at understanding the physiology of urea transport proteins, the renal inner medulla, and the urine-concentrating mechanism. His current research projects focus on defining the molecular physiology of urea transporters because urea transport is a key component in the urine-concentrating mechanism. These studies use rat and mouse models of abnormal concentrating and diluting ability, including genetically engineered mice.

Dr. Sands uses a combination of isolated perfused tubule studies to measure urea transport; antibodies to measure changes in the amount, phosphorylation, and localization of the urea transport proteins; Northern analysis and real-time polymerase chain reaction to measure changes in mRNA; and surface biotinylation and confocal microscopy to measure changes in the subcellular localization of urea transporters.

Dr. Sands has served as editor-in-chief of the American Journal of Physiology—Renal Physiology, as a councilor of the American Physiological Society, as chair of the 2004 American Society of Nephrology program committee, as chair of the Council on the Kidney of the American Heart Association, as a member of the board of scientific councilors of the National Institute of Diabetes and Digestive and Kidney Diseases, and as a member of the ASN publications and communications committee. He has served on study sections for the National Institutes of Health, American Heart Association, and National Kidney Foundation. He has published 139 original research papers, written 89 invited reviews and book chapters, and co-edited one book.

A graduate of Boston University School of Medicine, Dr. Sands trained in medicine at the University of Chicago and the National Heart, Lung, and Blood Institute, followed by a clinical nephrology fellowship at Emory.