Soil Screening Methods Uncover Potential New Antibiotic

New methods that extract drugs from soil bacteria have yielded a powerful new antibiotic, called teixobactin, that can cure severe gram-positive bacterial infections in mice with no adverse effects. Teixobactin inhibits cell wall synthesis by binding to a precursor of peptidoglycan and a precursor of cell wall teichoic acid. During their studies, investigators found no signs of any mutants of Staphylococcus aureus or Mycobacterium tuberculosis that became resistant to teixobactin. The findings are published in Nature

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New methods that extract drugs from soil bacteria have yielded a powerful new antibiotic, called teixobactin, that can cure severe gram-positive bacterial infections in mice with no adverse effects. Teixobactin inhibits cell wall synthesis by binding to a precursor of peptidoglycan and a precursor of cell wall teichoic acid. During their studies, investigators found no signs of any mutants of Staphylococcus aureus or Mycobacterium tuberculosis that became resistant to teixobactin. The findings are published in Nature

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