Program Seeks to Integrate Tissue Chips that Mimic Human Organ Functions

Researchers are working to refine 3-D human tissue chips and to combine them into an integrated system. Fifteen NIH institutes and centers are involved in coordinating the effort, which is called the Tissue Chip for Drug Screening program. One collaborative effort will share resources and expertise for the heart, blood vessel, and liver tissue chips. Another team will integrate the kidney, liver, gastrointestinal, and neural toxicity tissue chips. Two more project teams will develop platforms that mimic the human body’s natural environment and that can support 10 organ systems.

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Researchers are working to refine 3-D human tissue chips and to combine them into an integrated system. Fifteen NIH institutes and centers are involved in coordinating the effort, which is called the Tissue Chip for Drug Screening program. One collaborative effort will share resources and expertise for the heart, blood vessel, and liver tissue chips. Another team will integrate the kidney, liver, gastrointestinal, and neural toxicity tissue chips. Two more project teams will develop platforms that mimic the human body’s natural environment and that can support 10 organ systems.

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